The Port of Djibouti is a port in Djibouti City, the capital of Djibouti. It is strategically located at the crossroads of one of the busiest shipping routes in the world, linking Europe, the Far East, the Horn of Africa and the Persian Gulf. The port serves as a key refueling and transshipment center, and is the principal maritime outlet for imports to and exports from neighboring Ethiopia.

        The port evolved out of landlocked Ethiopia's search for a maritime outlet, and Djibouti’s coastline provided both easy access and sheltered anchorage. Work on the Franco-Ethiopian Ethio-Djibouti Railways began in 1897 and completed in 1917, connecting the Ethiopian capital of Addis Ababa to the port of Djibouti. The completion of the railway greatly increased business at the port.

        Development at the port increased further between 1948 and 1957 with the construction of four deep-water quays and the dredging of the port access channels. On land, new warehouses and oil storage facilities were built, electricity and water supplies provided and railway lines laid.

        Seventy percent of the cargo at the port is shipped to or from Ethiopia, accounting for over 95% of Ethiopia's foreign trade.The port lost its direct railway access to Ethiopia when the Ethio-Djibouti Railway was abandoned. The Addis Ababa–Djibouti Railway,runs to the nearby Port of Doraleh.